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Antigenic Specificity | IRF4 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF4 |
Other Names | [interferon regulatory factor 4 isoform a; Interferon regulatory factor 4; interferon regulatory factor 4; interferon regulatory factor 4; Lymphocyte-specific interferon regulatory factor; LSIRF; NF-EM5; PU.1 interaction partner; Transcriptional activator PIP] |
Gene, Accession # | [IRF4], Gene ID: 16364, NCBI: NP_038702.1, UniProt: Q64287 |
Catalog # | MBS3223600 |
Price | $335 |
Order / More Info | IRF4 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |