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Antigenic Specificity | BAK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BAK1 antibody detects endogenous levels of total BAK1. Description: Bak is a proapoptotic member of the Bcl-2 family (1). This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway (2, 3). Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death (4, 5).Function: Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial out |
Immunogen | Immunogen: N term-peptide of human BAK1 Subcellular Location: Mitochondrion Membrane. Tissue Specificity: Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle. |
Other Names | [Apoptosis regulator BAK; BAK; BAK like; BAK NT; BAK_HUMAN; BAK1; Bcl 2 homologous antagonist/killer; Bcl 2 like 7 protein; Bcl-2 homologous antagonist/killer; Bcl-2-like protein 7; BCL2 antagonist/killer 1; Bcl2 like 7 Protein; Bcl2-L-7; BCL2L7; CDN1; Cell death inhibitor 1; MGC117255; MGC3887; NBAK; Pro apoptotic protein BAK] |
Gene, Accession # | [BAK1], Gene ID: 578, NCBI: NP_001179.1, UniProt: Q16611 |
Catalog # | MBS9606681 |
Price | $240, $280 |
Order / More Info | BAK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |