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Antigenic Specificity | MUC2 (Mucin 2) |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
Immunogen | Immunogen: A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH. |
Other Names | [Mucin-2; Intestinal mucin-2; Mucin like protein (MLP); SMUC] |
Gene, Accession # | [MUC2], Gene ID: 4583, NCBI: NP_002448.2, UniProt: Q02817 |
Catalog # | MBS4381104 |
Price | $190, $340, $340 |
Order / More Info | MUC2 (Mucin 2) Antibody from MYBIOSOURCE INC. |
Product Specific References | Xing PX, et al. J Natl Cancer Inst. 1992; 84(9):699-703. |