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Antigenic Specificity | Bcl-2 |
Clone | [AT1B5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-2 (B-cell lymphoma protein 2 alpha) is an anti-apoptotic protein located primarily in the outer mitochondrial membrane. It blocks the apoptotic death of some cells such as lymphocytes. BCL-2 is thought to regulate cell death by controlling the mitochondrial membrane permeability during apoptosis. Bcl-2 protein has anti-apoptotic functions through inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
Immunogen | Immunogen: Recombinant human Bcl-2 (1-211aa) purified from E. coli |
Other Names | [B-cell lymphoma protein 2 alpha; B-cell lymphoma protein 2 alpha; B-cell lymphoma protein 2 alpha Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; Bcl-2; Bcl2; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma; B-cell; 2; Oncogene B-cell leukemia 2.], [BCL2; BCL2; Bcl-2; PPP1R50] |
Gene, Accession # | [Bcl-2], Gene ID: 596, NCBI: NP_000624, UniProt: P10415 |
Catalog # | MBS200190 |
Price | $240, $315 |
Order / More Info | Bcl-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Zamzami N., et al,. (1998) Oncogene. 16 (17):2265-82.; Fernandez-Sarabia MJ., et al,. (1993) Nature. 366 (6452):274-5. |