MEK4 (MAP2K4) (S257), 235-264 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MEK4 (MAP2K4) (S257), 235-264 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: Xenopus, mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.35 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MEK4(MAP2K4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from human MEK4(MAP2K4). MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. |
| Immunogen | n/a |
| Other Names | [Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKK; MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1] |
| Gene, Accession # | [MAP2K4], Gene ID: 6416, NCBI: NP_001268364.1, UniProt: P45985 |
| Catalog # | MBS9212008 |
| Price | $165, $370 |
| Order / More Info | MEK4 (MAP2K4) (S257), 235-264 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Robinson,V.L.,Mol. Cancer Res. 6 (3), 501-508 (2008) Zhang,H.,J. Biol. Chem. 282 (20), 14788-14796 (2007) Salmeron,A.,EMBO J. 15 (4), 817-826 (1996) |
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MYBIOSOURCE INC.
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