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Antigenic Specificity | p14 ARF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of p14 ARF protein. p14 ARF is induced in response to elevated mitogenic stimulation, such as aberrant growth signaling from MYC and Ras (protein). It accumulates mainly in the nucleolus where it forms stable complexes with NPM or Mdm2. These interactions allow p14ARF to act as a tumor suppressor by inhibiting ribosome biogenesis or initiating p53-dependent cell cycle arrest and apoptosis, respectively. |
Immunogen | Immunogen: p14 ARF antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human p14 ARF as the immunogen |
Other Names | [Purified p14 ARF; p14 ARF; p14 ARF; CDKN2; MLM; Cyclin-dependent kinase inhibitor 2A isoform 4; p14ARF; p19ARF] |
Gene, Accession # | [p14ARF] |
Catalog # | MBS5314150 |
Price | $270 |
Order / More Info | p14 ARF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |