Raf1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Raf1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mg |
| Concentration | 200 ug/ml |
| Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Human Raf1 is a proto oncogene encoded 74 kDa kinase that serves as an upstream activator of Mek1 by phosphorylating Ser 218 and Ser 222 in the MAP kinase kinase (Mek1). It has also been implicated in the phosphorylation and activation of the cdc2 tyrosine phosphatase cdc25. Raf1 binds to the GTP bound form of the Ras G protein via an N terminal domain in Raf 1. Raf 1 is activated upon phosphorylation by protein kinase C, Src and ceramide activated protein kinase. Raf 1 is highly related to the A Raf and B Raf isoforms within the N terminal G protein binding domain (CR1), phosphorylation site domain (CR2) and the catalytic domain (CR3). Raf 1 physically interacts with Ras, RapIB, MEK1, the 14 3 3 family of proteins and the molecular chapero |
| Immunogen | Immunogen: Raf1 antibody was raised in Rabbit using synthetic peptide mapping to the C-terminus of human Raf-1 as the immunogen. |
| Other Names | [Rabbit Raf1; Raf1; Raf1; Raf-1; Raf1; Raf 1; Raf-1; Raf 1; Raf-1] |
| Gene, Accession # | [Raf1], Gene ID: 5894, NCBI: AAA60247.1 |
| Catalog # | MBS5309057 |
| Price | $705 |
| Order / More Info | Raf1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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