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Antigenic Specificity | Human Orai1 (Extracellular) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Canis identical, bovine-12/13. Cytosolic calcium (Ca+2) has long been known to act as a key second messenger in many intracellular pathways including synaptic transmission, muscle contraction, hormonal secretion, cell growth and proliferation.1, 2 The mechanism controlling intracellular Ca+2 level influx either by the calcium-release-activated Ca+2 channels (CRAC), or from intracellular stores, has become of great interest. Recently, several key players of the store operated complex have been identified.3 Orai1 (also known as CRACM1) acts as the store operated calcium channel (SOC) and STIM1, which acts as the endoplasmic reticulum Ca+2 sensor.3, 4 The formation of functional channels by Orai1 requires the presence of both Orai |
Immunogen | Immunogen: Peptide (C)KKQPGQPRPTSK corresponding to residues of 203-214 of human Orai1 (Accession Q96D31). |
Other Names | [Orai] |
Gene, Accession # | [Orai1], Gene ID: 84876 |
Catalog # | MBS4159156 |
Price | $725 |
Order / More Info | Human Orai1 (Extracellular) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |