Sqstm1 (S351) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Sqstm1 (S351) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: rat) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.37 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351). Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. A |
| Immunogen | n/a |
| Other Names | [Sequestosome-1; STONE14; Ubiquitin-binding protein p62; Sqstm1; A170; STAP] |
| Gene, Accession # | [Sqstm1], Gene ID: 18412, NCBI: NP_001277698.1, UniProt: Q64337 |
| Catalog # | MBS9212103 |
| Price | $165, $370 |
| Order / More Info | Sqstm1 (S351) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ishii T.,et al.Biochem. Biophys. Res. Commun. 226:456-460(1996). Morris J.C.,et al.Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases. Carninci P.,et al.Science 309:1559-1563(2005). Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009). Ishii T.,et al.Biochem. Biophys. Res. Commun. 232:33-37(1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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