Mouse Cellular tumor antigen p53 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Cellular tumor antigen p53
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionActs as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage
ImmunogenImmunogen: Recombinant mouse Cellular tumor antigen p53 protein(1-387AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1313 / sc-1315
Other Names[Tumor suppressor p53; P53; Trp53; Tp53], [Trp53; Tp53; bbl; bfy; bhy; p44; p53; Tp53; P53; Trp53]
Gene, Accession #[p53], Gene ID: 22059, NCBI: NP_001120705.1, UniProt: P02340
Catalog #MBS1493871
Price$160, $235
Order / More InfoMouse Cellular tumor antigen p53 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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