DTL Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | DTL |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), FBXO18/FBH1 and KMT5A (PubMed: 16861906, PubMed: 16949367, PubMed: 16964240, PubMed: 17085480, PubMed: 18703516, PubMed: 18794347, PubMed: 18794348, PubMed: 19332548, PubMed: 20129063, PubMed: 23478441, PubMed: 23478445, PubMed: 23677613). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication (PubMed: 16861906, PubMed: 16949367, PubMed: 17085480). CDKN1A/p21(CIP1) degradatio |
| Immunogen | Immunogen: Recombinant Human Denticleless protein homolog protein (393-550AA) |
| Other Names | [Denticleless protein homolog; DDB1- and CUL4-associated factor 2; Lethal(2) denticleless protein homolog; Retinoic acid-regulated nuclear matrix-associated protein; DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP] |
| Gene, Accession # | [DTL], Gene ID: 51514, NCBI: NP_001273158.1, UniProt: Q9NZJ0 |
| Catalog # | MBS7051501 |
| Price | $160, $235 |
| Order / More Info | DTL Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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