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Antigenic Specificity | EPHA5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human EPHA5 (NP 004430.4). |
Other Names | [EK7; CEK7; EHK1; HEK7; EHK-1; TYRO4] |
Gene, Accession # | [EPHA5], Gene ID: 2044, NCBI: NP_004430.4, UniProt: P54756 |
Catalog # | MBS8549396 |
Price | $280 |
Order / More Info | EPHA5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |