TNFSF11 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNFSF11
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene
ImmunogenImmunogen: Recombinant protein of human TNFSF11 Immunogen Species: Human
Other Names[CD254; hRANKL2; ODF; OPGL; OPTB2; RANKL; sOdf; TNLG6B; TRANCE]
Gene, Accession #[TNFSF11], Gene ID: 8600, NCBI: NP_003692.1, UniProt: O14788
Catalog #MBS9133603
Price$200, $275, $430
Order / More InfoTNFSF11 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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