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Antigenic Specificity | Rat CD4 |
Clone | [W3/25] |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 0.1 mg, 0.5 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Functional Assay (FA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD4 (Rat CD4). anti-rat CD4 monoclonal antibody recognizes a determinant on the majority of thymocytes (90-95%), a subset of peripheral T cells and peritoneal macrophages. (1,2,3,10.) The antigen recognized by this antibody is a surface glycoprotein of Mr 48,000-52,000 and is the homologue of the human CD4 and the mouse L3/T4 antigen. MBS520105 labels the rat T helper subset, which mediates the helper activity for B and T cells, graft vs. host (GVH) reactivity and produces IL-2 in the mixed lymphocyte reaction (MLR). (2,4,6,) Addition of MBS520105 to the MLR, inhibited proliferation and blocks the production of IL-2. (4,5,6,9) T cells which mediate cytotoxicity and suppressor functions are not labelled. (Thus, cells labelled by |
Immunogen | Immunogen: Rat thymocyte membrane. Donor: BALB/c spleen. Fusion Partner: P3-NSI-1-Ag4 (NSI/1). |
Other Names | [CD4 Biotin (Clone W3/25) (mouse IgG1); Rat CD4], [CD4; CD4; CD4mut; CD4 receptor] |
Gene, Accession # | [CD4], Gene ID: 920, NCBI: CAA60883.1, UniProt: Q13969 |
Catalog # | MBS520105 |
Price | $250, $420 |
Order / More Info | Rat CD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |