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Antigenic Specificity | AKT1 |
Clone | [3A3] |
Host Species | Mouse |
Reactive Species | human, mouse, monkey |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. |
Immunogen | Immunogen: AKT1 antibody was raised in Mouse using a purified recombinant fragment of human AKT1 expressed in E Coli as the immunogen. |
Other Names | [Mouse AKT1; AKT1; AKT1; AKT1; AKT 1; AKT-1; AKT 1; AKT-1] |
Gene, Accession # | [AKT1], NCBI: AAL55732.1 |
Catalog # | MBS5310907 |
Price | $430 |
Order / More Info | AKT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |