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Antigenic Specificity | PIK3CG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phosphoinositide 3-kinase (PI3K) catalyzes the production of phosphatidylinositol-3, 4, 5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4, 5-bisphosphate (PIP2). Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration, and cell survival (1). PTEN reverses this process, and the PI3K signaling pathway is constitutively activated in human cancers that have loss of function of PTEN (2). PI3Ks are composed of a catalytic subunit (p110) and a regulatory subunit. Various isoforms of the catalytic subunit (p110alpha, p110beta, p110gamma, and p110delta) have been isolated, and the regulatory sub |
Immunogen | Immunogen: Recombinant protein of human PIK3CG Observed Molecular Weight: 126kDa |
Other Names | [PI3K; PIK3; PI3CG; PI3Kgamma] |
Gene, Accession # | [PIK3CG], Gene ID: 5294, NCBI: NP_001269356.1 |
Catalog # | MBS2518503 |
Price | $150, $225, $360 |
Order / More Info | PIK3CG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |