AKIR1 (C-term), 131-158 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AKIR1 (C-term), 131-158 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This AKIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the C-terminal region of human AKIR1. The highly conserved, nuclear-localized AKIRIN1 and Akirin2 proteins critically regulate the transcription of NF-kB dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kB pathways. AKIRIN1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for |
| Immunogen | n/a |
| Other Names | [Akirin-1; AKIRIN1; C1orf108] |
| Gene, Accession # | [AKIRIN1], Gene ID: 79647, NCBI: NP_001129747.1, UniProt: Q9H9L7 |
| Catalog # | MBS9202961 |
| Price | $165, $370 |
| Order / More Info | AKIR1 (C-term), 131-158 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Goto, A., et al. Nat. Immunol. 9(1):97-104(2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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