FBL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFBL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, monkey
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionS-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239).
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-321 of human FBL (NP 001427.2).
Other Names[FIB; FLRN; Nop1; RNU3IP1]
Gene, Accession #[FBL], Gene ID: 2091, NCBI: CAA39935.1, UniProt: P22087
Catalog #MBS8544253
Price$280
Order / More InfoFBL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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