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Antigenic Specificity | FBL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-321 of human FBL (NP 001427.2). |
Other Names | [FIB; FLRN; Nop1; RNU3IP1] |
Gene, Accession # | [FBL], Gene ID: 2091, NCBI: CAA39935.1, UniProt: P22087 |
Catalog # | MBS8544253 |
Price | $280 |
Order / More Info | FBL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |