PHF1 (N-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PHF1 (N-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PHF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 164-197 amino acids from the N-terminal region of human PHF1. Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Involved in DNA damage response and is recruited at double-strand breaks (DSBs). Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex. According to some reports, PRC2 recruitment by PHF1 promotes H3K27me3 and subsequent gene silencing by inducing spreading of |
| Immunogen | n/a |
| Other Names | [PHD finger protein 1; Protein PHF1; hPHF1; Polycomb-like protein 1; hPCl1; PHF1; PCL1] |
| Gene, Accession # | [PHF1], Gene ID: 5252, NCBI: NP_002627.1, UniProt: O43189 |
| Catalog # | MBS9207582 |
| Price | $165, $370 |
| Order / More Info | PHF1 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Coulson M.,et al.Genomics 48:381-383(1998). Wang J.H.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases. Mungall A.J.,et al.Nature 425:805-811(2003). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Micci F.,et al.Cancer Res. 66:107-112(2006). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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