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Antigenic Specificity | ERAP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1. The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3). |
Immunogen | Immunogen: ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. Buffer: ERAP2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ERAP2 : LRAP; L-RAP; LRAP; Endoplasmic reticulum aminopeptidase 2; Leukocyte-derived arginine aminopeptidase; endoplasmic reticulum aminopeptidase 2], [ERAP2; ERAP2; LRAP; L-RAP; LRAP; L-RAP] |
Gene, Accession # | [ERAP2], Gene ID: 64167, NCBI: NP_071745, UniProt: Q6P179 |
Catalog # | MBS153649 |
Price | $375 |
Order / More Info | ERAP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |