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Antigenic Specificity | IRF7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at le |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human IRF7. |
Other Names | [Interferon regulatory factor 7] |
Gene, Accession # | [IRF7], Gene ID: 3665, NCBI: NP_001563.2, UniProt: Q92985 |
Catalog # | MBS9402664 |
Price | $320 |
Order / More Info | IRF7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |