RAD50 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAD50 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD50
Other Names[DNA repair protein RAD50; DNA repair protein RAD50; DNA repair protein RAD50; RAD50 double strand break repair protein]
Gene, Accession #[RAD50], Gene ID: 10111, NCBI: NP_005723.2, UniProt: Q92878
Catalog #MBS3223196
Price$335
Order / More InfoRAD50 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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