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Antigenic Specificity | DFFA - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against DFFA. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DFFA |
Other Names | [DNA fragmentation factor subunit alpha isoform 1; DNA fragmentation factor subunit alpha; DNA fragmentation factor subunit alpha; DNA fragmentation factor subunit alpha; DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD] |
Gene, Accession # | [DFFA], Gene ID: 1676, NCBI: NP_004392, UniProt: O00273 |
Catalog # | MBS3200227 |
Price | $270 |
Order / More Info | DFFA - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |