Human Cytokine-inducible SH2-containing protein Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Cytokine-inducible SH2-containing protein |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Immunogen | Immunogen: Recombinant human Cytokine-inducible SH2-containing protein (1-257aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1529 / sc-1528 / sc-15344 |
| Other Names | [CIS; CIS-1; Protein G18; Suppressor of cytokine signaling; SOCS; CISH; G18], [CISH; CISH; CIS; G18; SOCS; CIS-1; BACTS2; G18; CIS; SOCS] |
| Gene, Accession # | [CISH], Gene ID: 1154, NCBI: NP_037456.5, UniProt: Q9NSE2 |
| Catalog # | MBS1493426 |
| Price | $120, $160 |
| Order / More Info | Human Cytokine-inducible SH2-containing protein Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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