Edit |   |
---|---|
Antigenic Specificity | Human EZRIN |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | dog (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti Human Ezrin antibody recognizes human ezrin, otherwise known as p81 or villin 2, Ezrin is a 586 amino acid ~80kDa cytoplasmic peripheral membrane protein containing a single FERM domain and member of the ezrin, radixin, moesin (ERM) protein family, which acts as protein-tyrosine kinase substrate. Ezrin is enriched in microvilli and other cell surface structures and plays a key role in cell surface structure adhesion, membrane trafficking, motility and organization (Ng et al. 2001). Ezrin acts as a linker protein between the plasma membrane and the actin cytoskeleton, and provides anchorage for cell surface molecules such as ICAM and CD44 (Finnerty et al. 2004). Studies have implicated ezrin in the metastatic capacity of various ty |
Immunogen | Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human ezrin was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [ezrin; Ezrin; ezrin; cytovillin 2; epididymis secretory protein Li 105; p81; villin 2 (ezrin); villin-2; ezrin; Cytovillin; Villin-2; p81], [EZR; EZR; CVL; CVIL; VIL2; HEL-S-105; VIL2] |
Gene, Accession # | [EZRIN], Gene ID: 7430, NCBI: NP_001104547.1, UniProt: P15311 |
Catalog # | MBS222872 |
Price | $550 |
Order / More Info | Human EZRIN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |