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Antigenic Specificity | GPR52 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GPR52 antibody detects endogenous levels of total GPR52. Description: Orphan receptor.Function: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).Similarity: Belongs to the G-protein |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Expressed in brain, especially in striatum. Predicted Cross Reactivity: Pig, Bovine, Xenopus Similarity: Pig (100%), Bovine (100%), Xenopus (83%) |
Other Names | [G protein coupled receptor 52; GPR52; GPR52_HUMAN; Probable G protein coupled receptor 52; Probable G-protein coupled receptor 52] |
Gene, Accession # | [GPR52], Gene ID: 9293, NCBI: NP_005675.3, UniProt: Q9Y2T5 |
Catalog # | MBS9604264 |
Price | $240, $280 |
Order / More Info | GPR52 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |