GPR52 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGPR52
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: GPR52 antibody detects endogenous levels of total GPR52. Description: Orphan receptor.Function: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).Similarity: Belongs to the G-protein
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Expressed in brain, especially in striatum. Predicted Cross Reactivity: Pig, Bovine, Xenopus Similarity: Pig (100%), Bovine (100%), Xenopus (83%)
Other Names[G protein coupled receptor 52; GPR52; GPR52_HUMAN; Probable G protein coupled receptor 52; Probable G-protein coupled receptor 52]
Gene, Accession #[GPR52], Gene ID: 9293, NCBI: NP_005675.3, UniProt: Q9Y2T5
Catalog #MBS9604264
Price$240, $280
Order / More InfoGPR52 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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