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Antigenic Specificity | Phospho-USP22 (Thr147) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-USP22(Thr147) Antibody detects endogenous levels of USP22 only when phosphorylated at Thr147. Description: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.Subunit Structure: Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ATXN7L3, ENY2 and USP22 form a subco |
Immunogen | Immunogen: A synthesized peptide derived from human USP22 around the phosphorylation site of Thr147. Tissue Specificity: Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver. |
Other Names | [Deubiquitinating enzyme 22; KIAA1063; Ubiquitin carboxyl terminal hydrolase 22; Ubiquitin carboxyl-terminal hydrolase 22; Ubiquitin specific peptidase 22; Ubiquitin specific peptidase 3 like; Ubiquitin specific processing protease 22; Ubiquitin specific protease 22; Ubiquitin thioesterase 22; Ubiquitin thiolesterase 22; Ubiquitin-specific-processing protease 22; UBP22_HUMAN; USP 22; Usp22; USP3L] |
Gene, Accession # | [USP22], Gene ID: 23326, NCBI: Q9UPT9.2, UniProt: Q9UPT9 |
Catalog # | MBS9610438 |
Price | $225, $280, $340 |
Order / More Info | Phospho-USP22 (Thr147) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |