TRIM29 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TRIM29 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TRIM29 antibody detects endogenous levels of total TRIM29. Function: Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of proinflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of TMEM173/STING in a similar way, leading to its degradation.Subunit Structure: Interacts with VIM and HINT1 (PubMed:7644499). Interacts with IKBKG/NEMO (PubMed:27695001). Interacts with TMEM173/STING (PubMed:29038422).Pos |
| Immunogen | Immunogen: A synthesized peptide derived from human TRIM29 Subcellular Location: Cytoplasm. Colocalizes with intermediate filaments. Tissue Specificity: Expressed in placenta, prostate and thymus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (90%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [Ataxia telangiectasia group D associated protein; Ataxia telangiectasia group D-associated protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing protein 29; Tripartite motif protein 29; Tripartite motif protein TRIM29; Tripartite motif-containing protein 29] |
| Gene, Accession # | [TRIM29], Gene ID: 23650, NCBI: NP_036233.2, UniProt: Q14134 |
| Catalog # | MBS9608519 |
| Price | $240, $280 |
| Order / More Info | TRIM29 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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