TRAIL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRAIL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionINPP5D, also named as SHIP, SHIP1, SIP-145 and hp51CN, belongs to the inositol-1, 4, 5-trisphosphate 5-phosphatase family. INPP5D is phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3, 4, 5-trisphosphate (PtdIns(3, 4, 5)P3) to produce PtdIns(3, 4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. INPP5D acts as a negative regulator of B-cell antigen receptor signaling. It mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. INPP5D acts as a negative regulator of myeloid cell proliferation/survival and chemotaxis, mast cell deg
ImmunogenImmunogen: A synthetic peptide of human INPP5D. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[SHIP; SHIP1; SHIP-1; hp51CN; SIP-145], [INPP5D; INPP5D; SHIP; SHIP1; SHIP-1; hp51CN; SIP-145; p150Ship; SHIP; SHIP1; SIP-145; SH2 domain-containing inositol phosphatase 1; SHIP-1; hp51CN]
Gene, Accession #[TRAIL], Gene ID: 3635, NCBI: NP_001017915.1, UniProt: Q92835
Catalog #MBS858544
Price$290
Order / More InfoTRAIL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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