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Antigenic Specificity | CaMK2-beta/ gamma/ delta (Phospho-Thr287) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of CaMK2- beta/ gamma/ delta only when phosphorylated at Threonine 287. Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic pl |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Threonine 287 |
Other Names | [CAM2, CAMK2, CAMKB] |
Gene, Accession # | [CaMK2-beta/ gamma/ delta], Gene ID: 816, NCBI: NP_001211.3, UniProt: Q13554 |
Catalog # | MBS9411684 |
Price | $200, $255 |
Order / More Info | CaMK2-beta/ gamma/ delta (Phospho-Thr287) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |