MYBBP1A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMYBBP1A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: MYBBP1A antibody detects endogenous levels of total MYBBP1A. Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.Subunit Structure: Binds to and represses JUN and MYB via the leucine zipper regions present in these proteins. Also binds to and represses PPARGC1A: this interaction is abrogated when PPARGC1A is phosphorylated by MAPK1/ERK. Binds to and stimulates transcriptio
ImmunogenImmunogen: A synthesized peptide derived from human MYBBP1A Subcellular Location: Cytoplasm. Nucleus. Nucleus > Nucleolus. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (89%)
Other Names[AL024407; AU019902; cb486; FLJ37886; MBB1A_HUMAN; MYB binding protein (P160) 1a; myb binding protein (P160) 1a like; Myb-binding protein 1A; Mybbp1a; nuclear protein P160; P160; p160MBP; p53 activated protein 2; p67MBP; PAP2; PAR interacting protein; RP23 48A2.3; sb:cb486]
Gene, Accession #[MYBBP1A], Gene ID: 10514, NCBI: NP_001099008.1, UniProt: Q9BQG0
Catalog #MBS9608813
Price$240, $280
Order / More InfoMYBBP1A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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