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Antigenic Specificity | MYBBP1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MYBBP1A antibody detects endogenous levels of total MYBBP1A. Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.Subunit Structure: Binds to and represses JUN and MYB via the leucine zipper regions present in these proteins. Also binds to and represses PPARGC1A: this interaction is abrogated when PPARGC1A is phosphorylated by MAPK1/ERK. Binds to and stimulates transcriptio |
Immunogen | Immunogen: A synthesized peptide derived from human MYBBP1A Subcellular Location: Cytoplasm. Nucleus. Nucleus > Nucleolus. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (89%) |
Other Names | [AL024407; AU019902; cb486; FLJ37886; MBB1A_HUMAN; MYB binding protein (P160) 1a; myb binding protein (P160) 1a like; Myb-binding protein 1A; Mybbp1a; nuclear protein P160; P160; p160MBP; p53 activated protein 2; p67MBP; PAP2; PAR interacting protein; RP23 48A2.3; sb:cb486] |
Gene, Accession # | [MYBBP1A], Gene ID: 10514, NCBI: NP_001099008.1, UniProt: Q9BQG0 |
Catalog # | MBS9608813 |
Price | $240, $280 |
Order / More Info | MYBBP1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |