CARD11 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCARD11
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total CARD11 protein. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.Bertin J., J. Biol. Chem. 276:11877-11882(2001).Gaide O., FEBS Lett. 496:121-127(2001).Hillier L.W., Nature 424:157-164(2003).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CARD11.
Other Names[Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 3; Carma 1; CARD11; CARMA1]
Gene, Accession #[CARD11], Gene ID: 84433, NCBI: NP_115791.3, UniProt: Q9BXL7
Catalog #MBS9413098
Price$200, $255
Order / More InfoCARD11 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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