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Antigenic Specificity | CARD11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CARD11 protein. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.Bertin J., J. Biol. Chem. 276:11877-11882(2001).Gaide O., FEBS Lett. 496:121-127(2001).Hillier L.W., Nature 424:157-164(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CARD11. |
Other Names | [Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 3; Carma 1; CARD11; CARMA1] |
Gene, Accession # | [CARD11], Gene ID: 84433, NCBI: NP_115791.3, UniProt: Q9BXL7 |
Catalog # | MBS9413098 |
Price | $200, $255 |
Order / More Info | CARD11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |