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Antigenic Specificity | Phospho-E2F1 (S332) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This E2F1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S332 of human E2F1. E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumo |
Immunogen | n/a |
Other Names | [Transcription factor E2F1; E2F-1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1; E2F1; RBBP3] |
Gene, Accession # | [E2F1], Gene ID: 1869, NCBI: NP_005216.1, UniProt: Q01094 |
Catalog # | MBS9215293 |
Price | $165, $370 |
Order / More Info | Phospho-E2F1 (S332) Antibody from MYBIOSOURCE INC. |
Product Specific References | O'Donnell, K.A., et al., Nature 435(7043):839-843 (2005). Wang, C., et al., J. Biol. Chem. 280(13):12339-12343 (2005). Joshi, B., et al., Oncogene 24(13):2204-2217 (2005). Saberwal, G., et al., Int. J. Hematol. 80(2):146-154 (2004). Chaussepied, M., et al., Mol. Cell 16(5):831-837 (2004). |