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Antigenic Specificity | bovine GFAP blocking Protein, against Rabbit GFAP RA22101 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | cat, human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human GFAP is a 49,749 dalton protein (432 amino acids) expressed in astrocytes. GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Various mutations of the GFAP gene in humans produce Alexander's disease, one of the leukodystrophies. Antibodies to GFAP are therefore very useful as markers of astrocytic cells and neural stem cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. |
Immunogen | Immunogen: Recombinant GFAP and purified bovine GFAP |
Other Names | n/a |
Gene, Accession # | [GFAP] |
Catalog # | MBS555587 |
Price | $350 |
Order / More Info | bovine GFAP blocking Protein, against Rabbit GFAP RA22101 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |