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Antigenic Specificity | Phospho-IRS2 (Y978) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IRS2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2. Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. |
Immunogen | n/a |
Other Names | [Insulin receptor substrate 2; IRS-2; IRS2] |
Gene, Accession # | [IRS2], Gene ID: 8660, NCBI: NP_003740.2, UniProt: Q9Y4H2 |
Catalog # | MBS9211379 |
Price | $165, $370 |
Order / More Info | Phospho-IRS2 (Y978) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hagg,D.A., Int. J. Mol. Med. 21 (6), 697-704 (2008) Platanias,L.C., J. Biol. Chem. 271 (1), 278-282 (1996) Sun,X.J., Nature 377 (6545), 173-177 (1995) |