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Antigenic Specificity | SLC12A5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (By similarity). Involved in the regulation of dendritic spine formation and maturation (PubMed:24668262). |
Immunogen | Immunogen: Recombinant Human Solute carrier family 12 member 5 protein (944-1071AA) |
Other Names | [Solute carrier family 12 member 5; Electroneutral potassium-chloride cotransporter 2; K-Cl cotransporter 2; hKCC2; Neuronal K-Cl cotransporter; SLC12A5; KCC2; KIAA1176] |
Gene, Accession # | [SLC12A5], Gene ID: 57468, NCBI: NP_001128243.1, UniProt: Q9H2X9 |
Catalog # | MBS7107555 |
Price | $160, $235 |
Order / More Info | SLC12A5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |