Edit |   |
Antigenic Specificity | CD100 (Semaphorin-4D) |
Clone | [A8] |
Host Species | Mouse |
Reactive Species | human, monkey, mouse. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation. |
Immunogen | Immunogen: PHA stimulated human peripheral blood lymphocytes |
Other Names | [COLL4; Collapsin4; GR3; M sema G; MSEMA; SEMA4D; Semacl2; SemaH; SEMAJ; Semaphorin C like 2; Semaphorin H; Semaphorin J; Semaphorin-4D; Semcl2], [SEMA4D; SEMA4D; CD100; SEMAJ; coll-4; C9orf164; M-sema-G; C9orf164; CD100; SEMAJ] |
Gene, Accession # | [SEMA4D], Gene ID: 10507, NCBI: NP_001135759.1, UniProt: Q92854 |
Catalog # | MBS438952 |
Price | $190, $340, $340 |
Order / More Info | CD100 (Semaphorin-4D) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hall K, et al. 1996. P. Natl. Acad. Sci. USA 93:11780. Mizrahi S, et al. 2007. PLoS One. 2(9):e818. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC) Schlossman SL Bloumsell W Gilks et al. eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press New York. Bougeret CIG Mansur H Dastot et al. 1992. Increased surface expression of a newly identified 150 kDa dimer early after human T lymphocyte activation. J. Immunol. 148:318. Knapp WB Dorken EP. Rieber et al, eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press New York |