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Antigenic Specificity | Human S-phase kinase-associated protein 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5 and probably NFKB2. SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of |
Immunogen | Immunogen: Recombinant human S-phase kinase-associated protein 1 protein(2-163AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1568 / sc-7163 |
Other Names | [Cyclin-A/CDK2-associated protein p19; p19A; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcription elongation factor B polypeptide 1-like; p19skp1; EMC19; OCP2; SKP1A; TCEB1L; SKP1], [SKP1; SKP1; OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L; EMC19; OCP2; SKP1A; TCEB1L; p19A; OCP-2; OCP-II] |
Gene, Accession # | [SKP1], Gene ID: 6500, NCBI: NP_008861.2, UniProt: P63208 |
Catalog # | MBS1492857 |
Price | $160, $235 |
Order / More Info | Human S-phase kinase-associated protein 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |