c-Myc (pSer373) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityc-Myc (pSer373)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRabbit anti c-Myc (pSer373) antibody recognizes proto-oncogene c-Myc, also known as Class E basic helix-loop-helix protein 39, transcription factor p64 and avian myelocytomatosis viral oncogene homolog, when phosphorylated at serine 373. c-Myc is a transcription factor and a member of the Myc family of basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factors. c-Myc is involved in regulation of the cell cycle, cell differentiation and apoptosis. Dimerization of c-Myc with bHLH-Zip protein Max is necessary for transcriptional activity (Nilsson and Cleveland 2003). c-Myc is phosphorylated at serine 373 by PAK2, this inhibits the ability of c-Myc to dimerize with Max, negatively regulating the activity of c-Myc (Huang et al. 2004)
ImmunogenImmunogen: Phospho specific-peptide corresponding to residues surrounding serine 373 of human c-Myc
Other Names[c-Myc (pSer373)], [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39]
Gene, Accession #[MYC], Gene ID: 4609, NCBI: P01106.1, UniProt: P01106
Catalog #MBS225221
Price$375
Order / More Infoc-Myc (pSer373) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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