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Antigenic Specificity | c-Myc (pSer373) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti c-Myc (pSer373) antibody recognizes proto-oncogene c-Myc, also known as Class E basic helix-loop-helix protein 39, transcription factor p64 and avian myelocytomatosis viral oncogene homolog, when phosphorylated at serine 373. c-Myc is a transcription factor and a member of the Myc family of basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factors. c-Myc is involved in regulation of the cell cycle, cell differentiation and apoptosis. Dimerization of c-Myc with bHLH-Zip protein Max is necessary for transcriptional activity (Nilsson and Cleveland 2003). c-Myc is phosphorylated at serine 373 by PAK2, this inhibits the ability of c-Myc to dimerize with Max, negatively regulating the activity of c-Myc (Huang et al. 2004) |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 373 of human c-Myc |
Other Names | [c-Myc (pSer373)], [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39] |
Gene, Accession # | [MYC], Gene ID: 4609, NCBI: P01106.1, UniProt: P01106 |
Catalog # | MBS225221 |
Price | $375 |
Order / More Info | c-Myc (pSer373) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |