BMI1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBMI1
Clone[282CT3.7.6]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1,k
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein. Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Immunogenn/a
Other Names[Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; PCGF4; RNF51]
Gene, Accession #[BMI1], Gene ID: 100532731, NCBI: NP_001190991.1, UniProt: P35226
Catalog #MBS9200047
Price$370
Order / More InfoBMI1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesIsmail, I.H., et al. J. Cell Biol. 191(1):45-60(2010) Yang, M.H., et al. Nat. Cell Biol. 12(10):982-992(2010) Kikuchi, J., et al. Cancer 116(12):3015-3024(2010) Honig, A., et al. Anticancer Res. 30(5):1559-1564(2010) Venkataraman, S., et al. PLoS ONE 5 (6), E10748 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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