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Antigenic Specificity | APPL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: APPL1 Polyclonal Antibody detects endogenous levels of APPL1 protein. The protein encoded by APPL1 has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human APPL1 at AA range: 90-170 |
Other Names | [Rabbit APPL1; APPL1; APPL; DIP13A; KIAA1428; DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1] |
Gene, Accession # | [APPL1], Gene ID: 26060, NCBI: NP_036228.1, UniProt: Q9UKG1 |
Catalog # | MBS9701417 |
Price | $130, $220, $325 |
Order / More Info | APPL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |