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Antigenic Specificity | Filamin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Filamin 1 Polyclonal Antibody detects endogenous levels of Filamin 1 protein. Filamin-A encoded by FLNA is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. Filamin-A is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. Filamin-A interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in FLNA are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding |
Immunogen | Immunogen: Synthesized peptide derived from human Filamin 1 around the non-phosphorylation site of S2152 |
Other Names | [Rabbit Filamin 1; FLNA; FLN; Filamin-A; FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin] |
Gene, Accession # | [FLN1], Gene ID: 2316, NCBI: NP_001104026.1, UniProt: P21333 |
Catalog # | MBS9702052 |
Price | $130, $220, $325 |
Order / More Info | Filamin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |