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Antigenic Specificity | CRTAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.3mg/mL |
Applications | ELISA; Western Blot (WB); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background/Introduction: Class-I MHC-restricted T cell associated molecule (CRTAM) is a receptor that is primarily expressed on activated cytotoxic lymphocytes, where it may play a role in their adhesion, interaction or migration. It is one of the most highly expressed surface markers detected on activated human NK T cells and CD8 T cells, suggesting its use as a diagnostic tool in various human viral and autoimmune diseases. CRTAM binds nectin-like protein 2 (necl2), which is involved in IL-22 expression regulation. This Necl2/CRTAM molecular pair may regulate cell/cell interactions and may play a role in neuronal interactions. CRTAM is also highly expressed in Purkinje neurons in the cerebellum. |
Immunogen | n/a |
Other Names | [CD355] |
Gene, Accession # | [CRTAM], Gene ID: 56253, NCBI: NP_001291711.1, UniProt: BC070266 |
Catalog # | MBS2524368 |
Price | $110, $150, $225 |
Order / More Info | CRTAM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |