IRF7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRF7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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DescriptionInterferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFNinducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3gamma/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ ICSBP. All IRF proteins share homology in their aminoterminal DNAbinding domains. IRF family members regulate transcription through interactions with proteins that share similar DNAbinding motifs, such as IFNstimulated response elements (ISRE), IFN consensus s
ImmunogenImmunogen: A synthetic -peptide of human IRF7
Other Names[IRF7; IRF7; IRF-7H; IRF7A; Interferon regulatory factor 7], [IRF7; IRF7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H; IRF-7]
Gene, Accession #Gene ID: 3665, NCBI: NP_001563.2, UniProt: Q92985
Catalog #MBS125545
Price$200, $275, $430
Order / More InfoIRF7 Antibody from MYBIOSOURCE INC.
Product Specific References1. Taniguchi, T. et al. (2001) Annu Rev Immunol 19, 623-55. 2. Honda, K. and Taniguchi, T. (2006) Nat Rev Immunol 6, 644-58. 3. Au, W.C. et al. (1998) J Biol Chem 273, 292-107. 4. Wathelet, M.G. et al. (1998) Mol Cell 1, 507-18. 5. Marie, I. et al. (1998) EMBO J 17, 6660-9. 6. Sato, M. et al. (2000) Immunity 13, 539-48. 7. Honda, K. et al. (2005) Nature 434, 772-7. 8. Colina, R. et al. (2008) Nature 452, 32-38. 9. Lin, R. et al. (2000) J Biol Chem 275, 34320-7. 10. Yang, H. et al. (2003) J Biol Chem 278, 15495-504. 11. Caillaud, A. et al. (2005) J Biol Chem 280, 17671-7.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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