DIS3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDIS3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: Multiple isoforms of DIS3 are known to exist. DIS3 Antibody: The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.
ImmunogenImmunogen: DIS3 antibody was raised against an 18 amino acid peptide near the amino terminus of human DIS3. Buffer: DIS3 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[DIS3; RRP44; dis3p; EXOSC11; KIAA1008; 2810028N01Rik; RRP44; Exosome complex exonuclease RRP44; Protein DIS3 homolog; DIS3 mitotic control homolog (S. cerevisiae)], [DIS3; DIS3; RRP44; dis3p; EXOSC11; KIAA1008; 2810028N01Rik; KIAA1008; RRP44]
Gene, Accession #[DIS3], Gene ID: 22894, NCBI: NP_055768, UniProt: Q9Y2L1
Catalog #MBS153622
Price$375
Order / More InfoDIS3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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