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Antigenic Specificity | WIPI-1 (Human) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human WIPI-1. WIPI-1 (WD-repeat protein interacting with phosphoinosides) is highly expressed in a variety of tumors. It interacts with phosphatidylinositol-3-P and this interaction is required for recruitment to membranes. WIPI-1 contains the signature motif LXXLL for nuclear receptor association and it binds to estrogen and androgen receptors in vitro. The WIPI-1 homolog in S. cerevisiae (Atg18) plays a role in autophagy. WIPI-1 accumulates in multi-membrane structures under autophagic conditions and it co-localizes with LC3. |
Immunogen | Immunogen: Synthetic peptide corresponding to aa of C-terminal human WIPI-1. |
Other Names | [WD repeat domain phosphoinositide-interacting protein 1; WD40 repeat protein interacting with phosphoinositides of 49kDa; Atg18 protein homolog; WIPI 49kDa], [WIPI1; WIPI1; ATG18; ATG18A; WIPI49; WIPI49; WIPI-1; WIPI 49 kDa] |
Gene, Accession # | [WIPI-1], Gene ID: 55062, NCBI: Q5MNZ9.3, UniProt: Q5MNZ9 |
Catalog # | MBS565300 |
Price | $345 |
Order / More Info | WIPI-1 (Human) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |