SLC22A17 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SLC22A17 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SLC22A17 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SLC22A17 antibody detects endogenous levels of total SLC22A17. Function: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. O |
| Immunogen | Immunogen: A synthesized peptide derived from human SLC22A17 Subcellular Location: Cell Membrane. Vacuole Membrane. Upon LCN2-binding, it is internalized. Tissue Specificity: Expressed in brain. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [24p3 receptor; 24p3R; BOCT; BOIT; Brain type organic cation transporter; Brain-type organic cation transporter; hBOIT; Lipocalin-2 receptor; Neutrophil gelatinase associated lipocalin receptor; Neutrophil gelatinase-associated lipocalin receptor; NGAL receptor; NgalR; NGALR2; NGALR3; OTTHUMP00000082690; OTTHUMP00000082691; Potent brain type organic ion transporter; S22AH_HUMAN; Slc22a17; Solute carrier family 22 member 17; Solute carrier family 22 organic cation transporter member 17] |
| Gene, Accession # | [SLC22A17], Gene ID: 51310, NCBI: NP_001275979.1, UniProt: Q8WUG5 |
| Catalog # | MBS9609605 |
| Price | $240, $280 |
| Order / More Info | SLC22A17 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies