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Antigenic Specificity | LRRFIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LRRFIP1 antibody is predicted to not cross-react with other LRRFIP family members. Three isoforms of LRRFIP1 are known to exist; this antibody will only recognize the two longer isoforms. LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate th |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 19 amino acid peptide near the carboxy terminus of human LRRFIP1. |
Other Names | [Leucine rich repeat interacting protein 1, TAR RNA-interacting protein, TRIP, FLAP-1, FLIIAP1, GC-binding factor 2, GCF2] |
Gene, Accession # | [LRRFIP1], Gene ID: 9208, NCBI: NP_001131022 |
Catalog # | MBS9404152 |
Price | $320 |
Order / More Info | LRRFIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |