SUV39H1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SUV39H1 |
| Clone | [42AT239.96.72] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.4 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SUV39H1 antibody was raised using purified recombinant GST fusion protein encoding N-terminal of human SUV39H1. This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. |
| Immunogen | n/a |
| Other Names | [Histone-lysine N-methyltransferase SUV39H1; Histone H3-K9 methyltransferase 1; H3-K9-HMTase 1; Lysine N-methyltransferase 1A; Position-effect variegation 3-9 homolog; Suppressor of variegation 3-9 homolog 1; Su(var)3-9 homolog 1; SUV39H1; KMT1A; SUV39H] |
| Gene, Accession # | [SUV39H1], Gene ID: 6839, NCBI: NP_001269095.1, UniProt: O43463 |
| Catalog # | MBS9200347 |
| Price | $165, $370 |
| Order / More Info | SUV39H1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output. Chen L, et al. EMBO J, 2010 Aug 4. PMID 20588255. EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization. Goyama S, et al. Leukemia, 2010 Jan. PMID 19776757. p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1. Cherrier T, et al. Oncogene, 2009 Sep 24. PMID 19581932. Inhibition of SUV39H1 methyltransferase activity by DBC1. Li Z, et al. J Biol Chem, 2009 Apr 17. PMID 19218236. A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a. Spensberger D, et al. FEBS Lett, 2008 Aug 6. PMID 18619962. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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