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Antigenic Specificity | Human TLR2 |
Clone | [IIG7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 0.1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TLR2 (Human TLR2 (CD282)). anti-human Toll-like Receptor 2 (TLR2) monoclonal antibody detects human TLR2 (CD282). This single membrane spanning, 784 amino acid, 90 KDa protein is a type of pattern recognition receptor (PRR) and recognizes structurally conserved microbial molecules as part of the innate immune response. TLR2 is activated in response to LPS (lipopolysaccharide) stimulation, resulting in NFkappaB activation and translocation. The TLR2 monoclonal antibody inhibits the production of inflammatory cytokines making it a selective inhibitor of TLR2 activation. TLR2 is expressed on peripheral blood macrophages, monocytes and leukocytes. This anti-body has been reported to work in Flow Cytometry, ELISA and Immunoprecipita |
Immunogen | Immunogen: Human TLR2. Donor: mouse ascites fluid |
Other Names | [TLR2, Biotin (Clone 11G7) (mouse IgG); Human TLR2 (CD282)], [TLR2; TLR2; TIL4; CD282; TIL4] |
Gene, Accession # | [TLR2], Gene ID: 7097, NCBI: NP_003255.2, UniProt: O60603 |
Catalog # | MBS520441 |
Price | $235 |
Order / More Info | Human TLR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |